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Why Did The Dishman Pharma Stock Fall by 14%?


Dishman Pharma hit a new low yesterday as they plummeted by more than 14%, the biggest single-fall since 24th August. The prime reason behind this sudden fall is because of the request made by FDA on one of it’s customers, Clovis Oncology, for more data on their awaited drug, Rociletinib, which is supposed to help treat lung cancer patients. Dishman’s Swiss subsidiary, Carbogen Amcis, was to make the API (Active Pharamaceutical Ingredient) for Clovis. 

FDA asked for more data confirmed responses(tumor shrinkage) in the clinical programme using Rociletinib. Clovis has been highlighting combined response rates – that is, both confirmed and unconfirmed responses to the drug – in its public stats, but apparently FDA will only look at confirmed responses. The stats point to a confirmed response rate of 28% in 79 patients using 500mg dose and a 34% confirmed response rate in 170 patients using 625mg dose of rociletinib, competitor AstraZeneca’s Tagrisso’s confirmed response rate is 59%.

Clovis shares fell 70% in the US on Monday, and a further 11% on Tuesday. Monday’s fall must have spooked investors and took it out on Dishman.

How did Dishman Pharma take the hit because of Clovis Oncology?

While Dishman Pharma’s VP of Finance Harshil Dalal explains that they do not expect any fiscal revenue from Rociletinib in 2016 or 2017, the fall had already taken place.

Deepak Shenoy explains the entire scenario with insights in the following video. Have a look to know more.

Update: Dishman CEO Clarifies, Stock Up On Wednesday

Dishman CEO JR Vyas has said (CNBC TV18 Interview) that all Clovis is expecting is a 3 month postponement of launch. Clovis could be in conversation with other suppliers of API. For Dishman, Clovis is not being factored into assumptions of revenue in the coming years. Clovis is anyhow likely to buy from multiple suppliers, not solely Dishman. 

The Dishman stock is up about 5% on wednesday. 

Sources: Forbes & Dishman Pharma’s response here.


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